Polymer infiltrated ceramic networks with biocompatible adhesive and 3D-printed highly porous scaffolds

Herein, for the first time is described design of a novel porous zirconia scaffolds manufactured by using polymer-infiltrated ceramic network (PICN) and 3D-printing technologies. Cubic geometry pieces was obtained perpendicular layer-by-layer deposition yttrium-stabilized tetragonal polycrystal (3Y-TZP) Pluronic® hydrogel paste. The specimens were prepared robocasting assembly with 50% infill pores, as feed setup. Bisphenol A glycerolate dimethacrylate (Bis-GMA) tri(ethylenglycol) (TEGDMA) copolymer, well-known biocompatible adhesive, which widely used in dentistry field, employed to reinforce pores 3D-printed structure. success acrylate polymer infiltration above scaffold surface among 3Y-TZP filaments achieved through previous functionalization 3-(trimethoxysilyl)propyl methacrylate (?-MPS). well material on evaluated gravimetry, obtaining value 87.5 ± 6.6% covered adhesive. Such successful copolymer had also positive effect mechanical properties material, being PICN sample that one highest elongation resistance. new system showed reduced bacteria proliferation, over 24 h incubation Gram-negative Escherichia coli Gram-positive Streptococcus salivarius lines, when compared control.